Comment: distinguishing post-kala-azar dermal leishmaniasis from leprosy: experience in the Sudan.
نویسنده
چکیده
In this study 4 patients were post-kala-azar dermal leishmaniasis (PKDL), whose lesions were similar to those of lepromatous and borderline leprosy, are described. In 2 patients there was no previous history of kala-azar but they were residents of an area of known endemic kala-azar. Lack of proper clinical and laboratory assessment was behind the failure to diagnose PKDL. Consequently the patients were treated with antileprosy drugs without proof of leprosy. The 3rd and 4th patients, though suspected clinically of leprosy, were correctly diagnosed as PKDL with adequate history, clinical assessment and appropriate laboratory investigations. The salient points in distinguishing PKDL from leprosy are described and discussed.
منابع مشابه
Post-kala-azar dermal leishmaniasis and leprosy: case report and literature review
BACKGROUND Post-kala-azar dermal leishmaniasis (PKDL) is a dermal complication of visceral leishmaniasis (VL), which may occur after or during treatment. It has been frequently reported from India and the Sudan, but its occurrence in South America has been rarely reported. It may mimic leprosy and its differentiation may be difficult, since both diseases may show hypo-pigmented macular lesions ...
متن کاملNerve involvement in Indian post kala-azar dermal leishmaniasis.
Sir, Post kala-azar dermal leishmaniasis (PKDL) is a wellrecognized sequel of kala-azar in India, developing in approximately 20% cases after a variable time interval of 1 – 5 years (1). The disease occurs chiefly in the eastern parts of India, an area that also has a high prevalence of leprosy. PKDL manifests as symmetrically distributed hypopigmented macules, papules, infiltrated plaques and ...
متن کاملTreatment-Based Strategy for the Management of Post-Kala-Azar Dermal Leishmaniasis Patients in the Sudan
UNLABELLED Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis that affects more than 50% of successfully treated visceral leishmaniasis (VL) patients in Sudan. PKDL is considered an important reservoir for the parasite and its treatment may help in the control of VL. Currently, treatment is mainly with sodium stibogluconate (SSG), an expensive and fairly toxic drug and without universal...
متن کاملSeptic Arthritis Caused by Streptococcus suis Serotype 5 in Pig Farmer
1. Rogers L. The epidemic malarial fever of Assam, or kala-azar, successfully eradicated from tea garden lines. Br Med J. 1898; 2:891–2. 2. Price JD, Rogers L. The uniform success of segregation measures in eradicating Kala-azar from Assam tea gardens: it is bearing on the probable mode of infection. BMJ. 1914;1:285–9. http://dx.doi. org/10.1136/bmj.1.2771.285 3. Kaul SM, Sharma RS, Borgohain B...
متن کاملleishmaniasis-current BurDen anD trenDs
Natural transmission of leishmaniasis is carried out by female sand flies. VL is a systemic disease characterised by prolonged fever, splenomegaly, hepatomegaly, weight loss, progressive anaemia, pancytopenia, and is complicated by serious infections. After recovery, some patients (50% in Sudan and 1 3% in India) develop post kala-azar dermal leishmaniasis (PKDL) characterised by depigmented ma...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Leprosy review
دوره 65 2 شماره
صفحات -
تاریخ انتشار 1993